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Molecular Biophysics

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Recent Honors

Congrats to Elijah Taylor
Elijah Taylor is a Molecular Biophysics Training Program trainee who is a winner of the 2021 NSF GRFP fellowship competition. He is in the Mondragon lab investigating the observation of type IA topoisomerase gate dynamics during DNA relaxation through combined single-molecule magnetic tweezers and FRET experiments. Congratulations Elijah!

Research Focus

Photo of Figure in Paper
Congratulations Siyu Chen and Anna Talyzina!
We are excited to share two recently published papers from the He lab that feature MBTP trainees Siyu Chen and Anna Talyzina. The paper in Nature focuses on using single particle Cryo-EM, in which they used to resolve two key states in the non-homologous end joining pathway that targets double-strand DNA breaks, and proposed a nearly complete reaction cycle of the pathway.  The Science paper focuses on using cryo-electron microscopy to investigate the structure of the human Mediator-bound PIC, which is important to Eukaryotic transcription.



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