Jason Brickner
Affiliation(s): Cell Biology of Transcription, IBiSj-brickner@northwestern.edu
Lab Website
The Brickner lab studies how cells control the position of genes within the nucleus, and how gene positioning affects gene expression.
Preceptors
Lin Chen
Affiliation(s): Chemistryl-chen@northwestern.edu
Lab Website
Jenna Christensen
Affiliation(s): IBiSjenna.christensen@northwestern.edu
Lab Website
The Christensen lab uses comparative biology and biochemical reconstitution to both understand fundamental principles behind intracellular transport and discover exceptions to these ‘rules’.
Paul DeCaen
Affiliation(s): PharmacologyThe DeCaen lab addresses the molecular and biophysical determinants ion channel disregulation in the disease state, and endeavor to characterize new ion channels and determine their context in cell physiology.
Juan Du
Affiliation(s): Department of Pharmacy at Feinberg School of Medicinejuan.du@northwestern.edu
Lab Website
We are broadly interested in how the human body senses external stimuli, conveys this signal to the brain and generates responses via neuronal ion channels, such as how we detect and respond to different temperatures.
Daniel Foltz
Affiliation(s): Biochemistry and Molecular Geneticsdfoltz@northwestern.edu
Lab Website
Alfred George
Affiliation(s): PharmacologyThe George lab studies the mechanisms by which ion channels mutations cause a variety of inherited disorders of membrane excitability including congenital cardiac arrhythmia, susceptibility, and epilepsy.
Songi Han
Affiliation(s): Chemistrysongi.han@northwestern.edu
Lab Website
Brian Hoffman
Affiliation(s): Chemistry, IBiSbmh@northwestern.edu
Lab Website
The Hoffman lab studies catalytic mechanisms of metalloenzymes through the development and implementation of ENDOR spectroscopy, NMR, and EPR.
Curt Horvath
Affiliation(s): Microbiology-Immunology, IBiShorvath@northwestern.edu
Lab Website
The Horvath lab studies signal transduction and gene regulation in innate immune responses to cancer and viruses.
Neha Kamat
Affiliation(s): Biomedical Engineering, IBiSnkamat@northwestern.edu
Lab Website
The Kamat lab studies artificial cell/protocell models, membrane biophysics, emergent behaviors from synthetic membranes, and membrane stress-sensing.
Neil Kelleher
Affiliation(s): Chemistry, IBiSn-kelleher@northwestern.edu
Lab Website
The Kelleher lab studies enzymology of natural product biosynthesis, mass spectrometric-based studies of the "Histone Code," and development of Fourier Transform Mass Spectrometry (FTMS) for Top Down Proteomics.
Laura Lackner
Affiliation(s): IBiSlaura.lackner@northwestern.edu
Lab Website
The Lackner lab studies dynamic interplay between the intracellular distribution of mitochondria and cellular function.
Hojoon Lee
Affiliation(s): IBiS, Neurobiologyhojoon.lee@northwestern.edu
Lab Website
Joshua Leonard
Affiliation(s): Chemical and Biological Engineering, IBiSj-leonard@northwestern.edu
Lab Website
The Leonard lab studies engineering cellular and biomolecular technologies for human health using synthetic biology and systems biology.
Julius Lucks
Affiliation(s): Chemical and Biological Engineering, IBiSjblucks@northwestern.edu
Lab Website
The Lucks lab studies unraveling the RNA sequence/structure/function code for biology, medicine, and biotechnology.
John Marko
Affiliation(s): Physics, IBiSjohn-marko@northwestern.edu
Lab Website
The Marko lab studies protein-DNA interactions, chromosome structure, and dynamics.
Alfonso Mondragón
Affiliation(s): IBiSThe Mondragon lab studies crystallographic elucidation of structure-function relationships of protein-nucleic acid interactions, and spectrin structure/function.
Richard Morimoto
Affiliation(s): IBiS, NUINr-morimoto@northwestern.edu
Lab Website
The Morimoto lab studies the heat-shock response and the transcriptional regulatory mechanisms of molecular chaperones.
Adilson Motter
Affiliation(s): Physicsmotter@northwestern.edu
Lab Website
Heather Pinkett
Affiliation(s): IBiSThe Pinkett lab studies how nutrients, antibiotics, and chemotherapeutics are transported into and out of the cell.
Murali Prakriya
Affiliation(s): DGP, NUIN, MSTPm-prakriya@northwestern.edu
Lab Website
The Prakriya lab studies the molecular and cellular mechanisms of intracellular calcium signaling.
Ishwar Radhakrishnan
Affiliation(s): IBiSi-radhakrishnan@northwestern.edu
Lab Website
The Radhakrishnan lab studies the transcription factor interactions in eukaryotic gene regulation using biological NMR spectroscopy.
Gabriel Rocklin
Affiliation(s): Center for Synthetic Biologygrocklin@northwestern.edu
Lab Website
The Rocklin lab develops high-throughput methods for protein biophysics and protein design, with a focus on protein therapeutics.
Amy Rosenzweig
Affiliation(s): IBiS, Chemistryamyr@northwestern.edu
Lab Website
Smriti Sangwan
Affiliation(s): Department of Pharmacologysmriti.sangwan@northwestern.edu
Lab Website
The Sangwan Lab studies the molecular basis of stress signaling using cryoEM with the goal of leveraging the structural information for targeted drug design.
Karla Satchell
Affiliation(s): Microbiology-Immunology, MSTPk-satchell@northwestern.edu
Lab Website
Krishna Shrinivas
Affiliation(s): Chemical and Biological Engineeringkrishna@northwestern.edu
Lab Website
The Shrinivas lab’s vision is to understand, and subsequently engineer, how biomolecules self-organize in cells to enable the diverse functions of life.
Wilton Snead
Affiliation(s): Cell and Developmental Biology, DGP, NUINwilton.snead@northwestern.edu
Lab Website
The Snead lab studies how proteins and RNAs self-assemble into biomolecular condensates, and how condensates shape gene expression in physiology and disease.
Danielle Tullman-Ercek
Affiliation(s): Chemical and Biological Engineering, IBiSercek@northwestern.edu
Lab Website
The Tullman-Ercek lab studies the engineering of membrane proteins and protein membranes.
Keith Tyo
Affiliation(s): Chemical and Biological Engineering, IBiSk-tyo@northwestern.edu
Lab Website
The Tyo lab investigates the regulation and biochemistry of metabolic networks, and toward manipulating the metabolic network to increase production of drugs, fuels, and chemicals.
Reza Vafabakhsh
Affiliation(s): IBiSreza.vafabakhsh@northwestern.edu
Lab Website
The Vafabakhsh lab studies the development of methods for quantitative hierarchical characterization of synaptic players at different length scales.
Sadie Wignall
Affiliation(s): IBiSs-wignall@northwestern.edu
Lab Website
The Wignall lab studies the mechanisms that promote accurate chromosome segregation during oocyte meiosis.
Frances Yap
Affiliation(s): Microbiology-Immunology, DGPfrances.yap@northwestern.edu
Lab Website
The Yap lab studies the biochemical and structural basis of mRNA translation and antibiotic resistance.
Josh Ziarek
Affiliation(s): Pharmacology, DGPjoshua.ziarek@northwestern.edu
Lab Website
The Ziarek lab is exploring the protein structure/function/dynamics relationship, molecular mechanisms of allostery, and the rational design of molecular therapeutics and tools – with a long-standing interest in G protein-coupled receptors (GPCRs).